Recommended treatment of paediatric tumours is misleading
نویسندگان
چکیده
منابع مشابه
Paediatric brain tumours.
Brain tumours constitute the most frequent solid tumour in childhood. At approximately 20% of paediatric malignant disease they remain uncommon with incidence of 2-3 per 100,000. Glial tumours represent over half of brain tumours in children, although in comparison with adult gliomas, where high grade tumours predominate, low grade tumours are more frequent. These characteristically include cys...
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The most important factor in terms of differential diagnosis of a new mass lesion in children is the child s age. In infancy, for example, congenital masses and many benign tumours are relatively common. As children grow older, the likely tumours vary with time. Some tumours, such as rhabdomyosarcomas, occur throughout childhood but most malignancies have relatively specific ages when their fre...
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Paediatric adrenocortical carcinoma is a rare malignancy with poor prognosis. Here we analyse 37 adrenocortical tumours (ACTs) by whole-genome, whole-exome and/or transcriptome sequencing. Most cases (91%) show loss of heterozygosity (LOH) of chromosome 11p, with uniform selection against the maternal chromosome. IGF2 on chromosome 11p is overexpressed in 100% of the tumours. TP53 mutations and...
متن کاملThe cytological diagnosis of paediatric renal tumours.
Fine needle aspiration cytology (FNAC) is used for preoperative diagnosis of paediatric renal tumours, especially in centres where preoperative chemotherapy is advocated in Wilms' tumour. This review focuses on salient cytological features in specific paediatric renal tumours, the approach to resolving a differential diagnosis and the role of ancillary methods in diagnosis of paediatric renal t...
متن کاملPaediatric orofacial tumours: new oral health concern in paediatric patients.
OBJECTIVE This study aims to determine the incidence, age, gender, orofacial sites and histological pattern of paediatric orofacial tumours in a Nigerian population. The yearly findings will be analysed to identify the interval for increase in the incidence of paediatric orofacial tumours. PATIENTS AND METHODS A 21-year (1990 to 2010) retrospective analysis of paediatric orofacial tumours in ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1996
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.313.7055.492a